Respiratory Syncytial Virus: Virology, Reverse Genetics, and ...
WEBHuman respiratory syncytial virus (RSV) is an enveloped, nonsegmented negative-strand RNA virus of family Paramyxoviridae. RSV is the most complex member of the family in terms of the number of genes and proteins. It is also relatively divergent and distinct from the prototype members of the family.
Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.
Viral vectored vaccines: design, development, preventive and ...
WEBApr 7, 2023 · Human respiratory syncytial virus (RSV) is the leading viral agent of severe acute respiratory infections in infants and young children worldwide. 171 Thus far, there is no licensed RSV...
Respiratory syncytial virus entry and how to block it
WEBFeb 5, 2019 · Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in young children and elderly people. Although the virus was isolated in 1955, an effective RSV...
A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus ...
WEBDec 22, 2020 · Packaging and prefusion stabilization separately and additively increase the quantity and quality of respiratory syncytial virus (RSV)-neutralizing antibodies induced by an RSV fusion protein expressed by a parainfluenza virus vector.
Respiratory Syncytial Virus Vaccines: A Review of the ... - PubMed
WEBOct 19, 2023 · The pipeline of RSV vaccine development includes messenger ribonucleic acid (mRNA), live-attenuated (LAV), subunit, and recombinant vector-based vaccine candidates targeting different virus proteins. The availability of vaccine candidates of various technologies enables adjustment to the individualized needs of …
Development of a reverse genetics system for respiratory syncytial ...
WEBAug 8, 2014 · Olson MR, Hartwig SM, Varga SM: The number of respiratory syncytial virus (RSV)-specific memory CD8 + T cells in the lung is critical for their ability to inhibit RSV vaccine-enhanced pulmonary eosinophilia.
Genetic diversity and molecular evolution of human respiratory ...
WEBJun 21, 2021 · Human respiratory syncytial virus (RSV) is a major cause of serious lower respiratory tract illness in infants, young children and the elderly in both industrialized and developing...
Respiratory syncytial virus prevention within reach: the vaccine …
WEBAug 8, 2022 · First-in-human randomized study to assess the safety and immunogenicity of an investigational respiratory syncytial virus (RSV) vaccine based on chimpanzee-adenovirus-155 viral vector-expressing RSV fusion, nucleocapsid, and …
A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus ...
WEBDec 22, 2020 · Live-attenuated pediatric vaccines for intranasal administration are being developed for human respiratory syncytial virus (RSV), an important worldwide pediatric respiratory pathogen that lacks a licensed vaccine or suitable antiviral drug. We evaluated a prime-boost strategy in which primary immun ….
Skip to content