NFC West foes San Francisco and Los Angeles face off again on Sunday. Here's what to know about one of the oldest rivalries ...

San Francisco 49ers tight end George Kittle will miss Sunday's game against the Los Angeles Rams because of a hamstring ...

Suddenly in doubt for the Week 3 game at L.A. are tight end George Kittle, defensive end Nick Bosa, and cornerback Charvarius ...

Kyle Shanahan told NBC Sports Bay Area’s Greg Papa on “49ers Game Plan" that rookie running back Isaac Guerendo could be set ...

Also likely to be out is tight end George Kittle, who is doubtful and battling a hamstring issue. That will further ding the ...

The 49ers have listed George Kittle as doubtful to play this Sunday against the Los Angeles Rams. That means backup tight end ...

Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...

Earlier this week, 49ers head coach Kyle Shanahan said he doesn't ask Brock Purdy to do too much on the field. That was an understatement. Shanahan doesn't all ...

Running back Isaac Guerendo is fast. And he's big. But the San Francisco 49ers rookie is a work in progress. His lone carry ...

In Week 3, the Los Angeles Rams will face the San Francisco 49ers. This will be Jimmy Garoppolo's first game as part of the Rams' main roster, as he was suspended for the first two games of the season ...

The recent retirement of Aaron Donald, the three-time Defensive Player of the Year and a key figure in the Rams' defense, has ...

The last time the Los Angeles Rams and San Francisco 49ers met, head coaches Sean McVay and Kyle Shanahan were without some ...