The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

The 49ers woes in Minnesota continued last week when their former quarterback Sam Darnold torched his old squad. The offense ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

The New York Jets suffered a rough loss in Week 1 of the 2024 NFL regular season to the San Francisco 49ers. What started off ...

Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...

The San Francisco 49ers look to rookie Jacob Cowing to exploit defensive mismatches and invigorate the offense ...

Do we have a revenge game on our hands in NFL Week 2? Sam Darnold – the San Francisco 49ers backup quarterback last season – ...